PDF Ebook Life from an RNA World: The Ancestor Within, by Michael Yarus
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Life from an RNA World: The Ancestor Within, by Michael Yarus
PDF Ebook Life from an RNA World: The Ancestor Within, by Michael Yarus
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Review
offers an invaluable vision of life..before DNA and proteins...enjoyable to read, easy to understand..will appeal to readers with a strong interest in evolution and molecular biology. --Current Reviews for Academic Libraries -H. Zhou, Seton Hall U.So, should you buy this book and read it? Yes -- if you have any interest in molecular evolution you will be enlivened, informed and amused. Will you get definitive proof of the RNA world? No -- as Elvis Costello said, it's 'still too soon to know' - John Sutherland, Nature Chemistry 2: 603 (2010).. those items are what I most liked about the book. Other readers will likely find other gems and insight in what is an accessible account of "Life from an RNA World". - Arthur G. Hunt, Reports of the National Center for Science Education, 2011.
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About the Author
Michael Yarus is Professor Emeritus, Department of Molecular, Cellular, and Developmental Biology, University of Colorado.
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Product details
Paperback: 208 pages
Publisher: Harvard University Press; Reprint edition (March 18, 2011)
Language: English
ISBN-10: 0674060717
ISBN-13: 978-0674060715
Product Dimensions:
5.5 x 0.8 x 8.2 inches
Shipping Weight: 8.8 ounces (View shipping rates and policies)
Average Customer Review:
3.6 out of 5 stars
10 customer reviews
Amazon Best Sellers Rank:
#1,238,289 in Books (See Top 100 in Books)
Im not sure what prompted me to buy this, I think it was a recommendation for having bought Wetware. This book is about RNA and some of its complexity and properties. In this exploration, or overview perhaps, it is argued that RNA if properly considered can potentially fill in many of our gaps in understanding about the origin of life. In reading this book, I got a perspective on not only RNA but what pioneering biologists work on to build a framework for understanding the origin of life. There are a lot of computational biology ideas that seem embedded in the experiments done and ideas used. For example the book starts out with defining the differences between organisms RNA as a metric on genetic difference. In addition there are some real life genetic programming experiments that are done with putting in various combinations of nucleotides and then letting the mixtures self select the best solutions. I am a bit mixed on the book as a whole as it is supposedly written for a general audience, but there is a substantial amount of the book that requires a lot of understanding of cell biology (which I dont have) and logic chains are used with a need for very specific knowledge that the audience of this book is really not what is claimed.The first 2/3 of the book I was able to follow more thoroughly, it is presented in short chapters about specific topics. Some of these are very understandable by a wide audience, they talk about intelligent design, plausibility of RNA's place in evolution, how to define life etc... The chapters end with specific references which allow the interested reader to explore further the topics considered. However, as one gets further through the book, the ability to follow becomes harder and harder for the non-expert. The reference become 100% journal articles which to be honest, are obviously not for general audience, and the arguments used for and agaisnt are very specific, needing a solid backgrouond in what I think is deeper than an undergraduate experience in biology.All in all, if one is interested in cell biology and evolution and some of the complexity and properties of biologicial phenomenon, this gives a lot of food for thought. But this book is definitely mainly written for people who already know the topics the author is discussing, not for a person with casual interests in the subject. This book argues I think quite convincingly about the plausibility of RNA as the origin of selp replicating organic matter, but after reading this without a strong background, one is not in a position to truly appreciate the arguments properly.
I bought it based on a review in Science. And also because I am a "beginning of life" nut: I own a good chunk of Stanley Miller's personal library. There were some interesting tidbits and I did learn quite a bit. However, the writer sometimes seems to forget his target audience: some chapters are so elementary that they seem written for a middle schooler, others are so technical that only a specialist can grasp them. When you use a new term: define it! The lexicon at the end is somewhat useful but not fully adequate. Also, a couple of chapters read a bit too much like an infomercial for SELEX. I am sure it is powerful, but it can't so wonderful that no mistakes are ever made and results can be taken at face value without independent corroboration. Overall, a good intro to the RNA world, but comes up short.
Very interesting as it provides insight to the evolution of evolution
Purchased this book after hearing about it in either Science or Nature. As a microbiology major, I found the book to be well-written and extremely interesting. I would, however recommend this book more to people who have prior background knowledge in microbiology as the book crams a lot of detail into small chapters, glossing over what the author assumes that the reader is familiar with. The end of chapter further reading recommendations were a nice added touch to allow the reader to further investigate topics of interest.
the chapters i've read are ok, i just got it for a class at college so...
Pretty much everyone in the literate world has learned that DNA encodes the blueprint of every living being. Then, when people learn a little more, they hear how RNA carries DNA's message out to the working machinery of the cell. True, as far as it goes, but that hardly does justice to this remarkable molecule.RNA acts not only as information carrier, but as mechanism as well - it can catalyze reactions all by itself, including the replication of new RNA. Yarus weaves this story without technobabble, and with reference to many of the chemical investigations into life's origins. He notes how readily RNA interacts with all the other building blocks of life, and points to believable chemical reactions that could have brought it into existence. This is all conjecture of course - only an observer at the scene could say what really happened, and no such being exists. But, despite Yarus' slight abuse of Bayes' theorem, each partial explanation of one facet of that world makes the whole idea even more credible.Yarus notes that the laws of chemistry make mutation inevitable. Replication, competition for resources (such as nutrients), and change over time: Darwinian evolution becomes inevitable even in that world. He also keeps a tight focus on RNA's potential as the ancestor of out DNA/protein life. As a result, he skips over many of RNA's recently discovered capabilities. He also skips some of the other chemical mechanisms that could have been at work in the pre-life world, mechanisms that complement RNA's self-replication and describe other features of cellular life. Life's origin is too big a story to tell all at once, though, and Yarus does an outstanding and approachable job with this fascinating chapter of that story.-- wiredweird
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